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- Season 0 1998-09-16
- Season 1 1993-09-13
- Season 2 1994-09-12
- Season 3 1995-09-11
- Season 4 1996-09-17
- Season 5 1997-09-09
- Season 6 1998-09-15
- Season 7 1999-09-07
- Season 8 2000-09-05
- Season 9 2001-09-04
- Season 10 2002-09-03
- Season 11 2003-09-03
- Season 12 2004-08-31
- Season 13 2005-09-06
- Season 14 2006-09-05
- Season 15 2007-09-04
- Season 16 2008-09-02
Season 16 Episode
- Season 14 Julianne Moore, Aries Spears, Godsmack
- Season 14 David Duchovny, Greg Behrendt, OK Go
- Season 14 Kiefer Sutherland, Joely Fisher, Ben Harper
- Season 14 Alan Alda, Sophia Bush, Citizen Cope
- Season 14 Zach Braff, Artie Lange, John Mayer
- Season 14 Ashton Kutcher, Tracy Morgan, John Mayer
- Season 14 Dwayne "The Rock" Johnson, Al Franken, air guitar expert Björn Türoque
- Season 14 Matthew Perry, Xzibit, The Rapture
- Season 14 Gisele Bundchen, Jim Cramer, Madeleine Peyroux
- Season 14 Johnny Knoxville, Caroline Rhea, Bonnie "Prince" Billy
- Season 14 Bob Newhart, Elle Macpherson, Jimmy Carr
- Season 14 Jennifer Love Hewitt, John Krasinski, Ben Kweller
- Season 14 Jason Lee, Bridget Moynahan, Chingy
- Season 14 Marcia Cross, David Gregory, Sam Moore
- Season 14 Christopher Walken, Michael Clarke Duncan, Scissor Sisters
- Season 14 Billy Bob Thornton, Mr. T, The Wreckers
- Season 14 John Stamos, Amy Poehler, Nigella Lawson
- Season 14 Bob Costas, David Cross, Phoenix
- Season 14 Dennis Miller, Rachael Ray, Evanescence
- Season 14 Martin Scorsese, Harland Williams, The Decemberists
- Season 14 Brian Williams, Scott Wolf, Larry Miller
- Season 14 Jaime Pressly, Jerome Bettis, Jerry Lee Lewis
- Season 14 Alex Trebek, Yunjin Kim, Barenaked Ladies
- Season 14 John Lithgow, Lewis Black, Gomez
- Season 14 Alec Baldwin, John Cena, Demetri Martin
- Season 14 Sarah Michelle Gellar, Bob Saget, Robert Randolph & The Family Band
- Season 14 Helen Mirren, Jim Gaffigan, Basement Jaxx
- Season 14 Jason Schwartzman, Arielle Kebbel, Jenny Lewis
- Season 14 Regis Philbin, Alessandra Ambrosio, Dierks Bentley
- Season 14 Tina Fey, Steven Wright, Barbara Stewart
- Season 14 Kirsten Dunst, Harry Shearer, Corinne Bailey Rae
- Season 14 Nathan Lane, Jason Sudeikis, Ben Folds
- Season 14 Diddy, Joe Buck, Frank Black
- Season 14 Charles Barkley, Kristin Chenoweth, Cat Power
- Season 14 The Skeleton Show
- Season 14 Borat, Jack McBrayer, Mastodon
- Season 14 John Leguizamo, Arden Myrin, Los Abandoned
- Season 14 Darrell Hammond, Jesse Bradford, Prof. Kevin Warwick
- Season 14 Russell Crowe, Jorge Garcia, Dean Karnazes
- Season 14 Will Ferrell, Tom Everett Scott, Death Cab For Cutie
- Season 14 Howie Mandel, James Lipton, Mat Kearney
- Season 14 Meredith Vieira, Greg Grunberg, Old Crow Medicine Show
- Season 14 Barbara Walters, Dax Shepard, Los Lobos
- Season 14 Robin Williams, Christian Slater, Panic! At The Disco
- Season 14 Jack Black & Kyle Gass, Joshua Jackson, Tenacious D
- Season 14 Elijah Wood, Jon Lovitz, Jud Hale
- Season 14 Martin Short, Flavor Flav, Damien Rice
- Season 14 Rachel Weisz, Masi Oka, Army of Anyone
- Season 14 James Spader, Amy Sedaris, Robyn Hitchcock
- Season 14 Will Arnett, Alyson Hannigan, Billy Talent
- Season 14 Ethan Hawke, Jim Gaffigan, The Brand New Heavies
- Season 14 Hugh Jackman, Tiki Barber, Mike Birbiglia
- Season 14 Matthew Broderick, Lisa Edelstein, Jet
- Season 14 Jude Law, Kristen Wiig, The Brian Setzer Orchestra
- Season 14 Martha Stewart, Brian Posehn, My Morning Jacket
- Season 14 Lucy Liu, Tillie the Canine Artist
- Season 14 Tom Brokaw, Ed Helms, Sarah McLachlan
- Season 14 Jennifer Connelly, Jason Segel, Joan Jett and the Blackhearts
- Season 14 Kevin Nealon, Angela Kinsey, Deftones
- Season 14 Rob Lowe, Rashida Jones, Drake Bell
- Season 14 Julianna Margulies, Aries Spears, Mike Lupica
- Season 14 Chazz Palminteri, Seth Meyers, TV On The Radio
- Season 14 Cameron Diaz, Dennis Haysbert, Dashboard Confessional
- Season 14 Ricky Gervais, Steven R. Schirripa, The Matt Savage Trio
- Season 14 Jeremy Irons, Terry Crews, Aimee Mann
- Season 14 Howard Stern, Jim Gaffigan
- Season 14 Sylvester Stallone, Carla Gugino, Matt Mays & El Torpedo
- Season 14 Patricia Heaton, Jason Ritter, Tony Bennett
- Season 14 Ben Stiller, Ving Rhames, Joshua Bell
- Season 14 Andy Samberg, Stuart Scott, Sean Lennon
- Season 14 Ewan McGregor, Manny Puig, Jordana Spiro
- Season 14 Carson Daly, Michelle Trachtenberg, Nellie McKay
- Season 14 LL Cool J, Abigail Breslin, Gov't Mule
- Season 14 Placido Domingo, Patton Oswalt, moe.
- Season 14 Jarod Miller, Dulé Hill, Louis C.K.
- Season 14 Cedric the Entertainer, Orlando Jones, John Pizzarelli
- Season 14 Matt Lauer, America Ferrera, Little Big Town
- Season 14 Donald Trump, Meagan Good, Ron Sexsmith
- Season 14 David Arquette, Lonny Ross, Chuck "The Iceman" Liddell
- Season 14 Hilary Swank, Artie Lange, The Black Keys
- Season 14 Kiefer Sutherland, Jill Hennessy, Gym Class Heroes
- Season 14 Tracy Morgan, Jim Gaffigan, Sparta
- Season 14 Brian Williams, Dominic Purcell, Dana Gould
- Season 14 Megan Mullally, Colin Hanks, Annuals
- Season 14 Liam Neeson, Ali Larter, Brand New
- Season 14 Brad Garrett, Sarah Silverman, Peter Bjorn And John
- Season 14 Kristin Davis, Bob Saget, Paolo Nutini
- Season 14 Sienna Miller, Goran Visnjic, Paul Weller
- Season 14 Serena Williams, Donal Logue, Kevin Brennan
- Season 14 Charlize Theron, Bill Hader, Stars of Track and Field
- Season 14 Kristin Chenoweth, Mindy Kaling, The Slip
- Season 14 Dr. Phil McGraw, Emily Deschanel, Calexico
- Season 14 Cuba Gooding Jr., Joy Behar, Jonathan Katz
- Season 14 Bob Costas, Ashley Tisdale, Josh Groban
- Season 14 Dylan McDermott, Michael Urie, Lamb of God
- Season 14 Martin Lawrence, Hayden Panettiere, Hinder
- Season 14 Eva Longoria, Fred Willard, Lily Allen
- Season 14 Drew Barrymore, Marc Maron, The Apples in Stereo
- Season 14 Nicolas Cage, Natalie Morales, John Mulaney
- Season 14 Christina Ricci, Alan Cumming, Joshua Radin
- Season 14 Sen. Chuck Schumer, Tracee Ellis Ross, The Holmes Brothers
- Season 14 Heather Graham, Lewis Black, Explosions in the Sky
- Season 14 Jim Carrey, Al Roker, Jonny Lives!
- Season 14 Jimmy Fallon, Keith Olbermann, Steven Kaplan
- Season 14 Billy Bob Thornton, J. Alexander, G. Love
- Season 14 Jim Gaffigan, Liev Schrieber, Solomon Burke
- Season 14 Jake Gyllenhaal, Lance Armstrong, Bayside
- Season 14 Larry King, Izabel Goulart, 'Biscuit Lady' Carol Fay
- Season 14 Anderson Cooper, Rob Corddry, Son Volt
- Season 14 Ted Koppel, Tom Cavanagh, Relient K
- Season 14 David Hyde Pierce, Kate Mara, Dr. Dog
- Season 14 Chris Rock, Christopher Meloni, Mary Weiss with The Reigning Sound
- Season 14 Andy Richter, Len Berman, The Shins
- Season 14 Julia Louis-Dreyfus, Harland Williams, Neil deGrasse Tyson
- Season 14 Jeff Goldblum, Ivanka Trump, Pete Yorn
- Season 14 Tom Arnold, Rainn Wilson, Jesse Malin
- Season 14 Bernie Mac, Chris Hansen, Daughtry
- Season 14 Don Cheadle, Neil Patrick Harris, Shane Mauss
- Season 14 Adam Sandler, Sarah Thyre, Lindsey Buckingham
- Season 14 Liv Tyler, Gerard Butler, The Fratellis
- Season 14 Quentin Tarantino, Jesse L. Martin, Brian Kiley
- Season 14 Rosario Dawson, Jason Sudeikis, Martina McBride
- Season 14 Ice Cube, B.J. Novak, Clap Your Hands Say Yeah
- Season 14 Diddy, David Gregory, Kaiser Chiefs
- Season 14 Michael Imperioli, Jim Cramer, Albert Hammond, Jr.
- Season 14 Jeff Daniels, Zoë Bell, The Alternate Routes
- Season 14 Martin Short, Cheryl Hines, Cold War Kids
- Season 14 Tina Fey, Kevin Pollack, Mystery
- Season 14 Molly Shannon, Tiki Barber, Of Montreal
- Season 14 Ray Liotta, Mary Lynn Rajskub, Joseph Arthur
- Season 14 Martha Stewart, Rob Huebel, Ian Edwards
- Season 14 Darrell Hammond, Andrew W.K., Blue October
- Season 14 Tyra Banks, Masi Oka, Brandi Carlile
- Season 14 Garry Shandling, Adam Brody, Ricky Skaggs & Bruce Hornsby
- Season 14 Dana Carvey, Jasper Redd, Arctic Monkeys
- Season 14 George Lucas, Will Arnett, Chris Isaak
- Season 14 Robin Williams, The Glide Ensemble
- Season 14 Randy Jackson, Patton Oswalt, Frisbee Golf National Champion David Feldberg, Bob Weir & RatDog
- Season 14 Snoop Dogg, Tom Waits
- Season 14 Amanda Peet, Morgan Spurlock, Secondhand Serenade
- Season 14 Zach Braff, D. J. Qualls, Jimmy Carr
- Season 14 Howie Mandel, Criss Angel, Patrick Wolf
- Season 14 Lindsay Lohan, Larry the Cable Guy, Stephen Marley featuring Damien
- Season 14 Antonio Banderas, Sarah Chalke, The Avett Brothers
- Season 14 William Shatner, Eric Dane, mtvU's Best Music on Campus Winner
- Season 14 Tom Selleck, John Stamos, Dan Mintz
- Season 14 Rebecca Romijn, Donald Faison, Silversun Pickups
- Season 14 Amy Poehler, Dave Annable, M. Ward
- Season 14 Luke Wilson, Oscar Nuñez, Blonde Redhead
- Season 14 Dominic Monaghan, Chris 'Ludacris' Bridges, Rickie Lee Jones
- Season 14 Amy Sedaris, Lester Holt, Loudon Wainwright III
- Season 14 America Ferrera, Eddie Izzard, Mark 'Dr. Bugs' Moffett
- Season 14 Mike Myers, Seth Rogen, The Academy Is...
- Season 14 Dane Cook, 'Dancing With the Stars' winner Apolo Anton Ohno, Mando Diao
- Season 14 Paul Rudd, Elisha Cuthbert, Kings of Leon
- Season 14 Brian Williams, Leslie Mann, Los Straitjackets with Big Sandy
- Season 14 Debra Messing, Marc Maron, Nelly Furtado
- Season 14 Marg Helgenberger, Steven R. Schirripa, John Mulaney
- Season 14 Nicole Richie, Billy Connolly, Crowded House
- Season 14 Seth Green, Eli Roth, EL-P
- Season 14 Tim Russert, Ginnifer Goodwin, Feist
- Season 14 Kevin Dillon, Jim Cramer, Patty Griffin
- Season 14 Kyra Sedgwick, John Cena, Andrew Bird
- Season 14 Jessica Alba, Bear Grylls, Paul F. Tompkins
- Season 14 Tea Leoni, Tyrese Gibson, The White Stripes
- Season 14 Steve Carell, Jennifer Esposito, Flight of the Conchords
- Season 14 Wanda Sykes, Nick Offerman, illusionist Hans Klok with Pamela Anderson
- Season 14 John Krasinski, Louis CK, The Mooney Suzuki
- Season 14 Lauren Graham, Steve Zahn, Rooney
- Season 14 Jarod Miller, Jason Priestley, Dan Naturman
- Season 14 Denis Leary, Mark Consuelos, Against Me!
- Season 14 Daniel Radcliffe, Carlos Mencia, Art Brut
- Season 14 Emma Watson, Patton Oswalt, Mark Ronson
- Season 14 Jason Sudeikis, Janeane Garofalo, They Might Be Giants
- Season 14 Christopher Walken, Tim Meadows, Nick Lowe
- Season 14 Jessica Biel, Artie Lange, The Cribs
- Season 14 Adam Sandler, Vera Farmiga, Pegi Young
- Season 14 Queen Latifah, Matt Groening, Fountains of Wayne
- Season 14 Kevin James, Jordana Spiro, Greg Giraldo
- Season 14 John Leguizamo, James Blake, Marc Broussard
- Season 14 Andy Samberg, Harry Shearer, Tegan & Sara
- Season 14 Seth Rogen, Ann Curry, wine expert Gary Vaynerchuk
- Season 14 Anne Hathaway, Harland Williams, Mavis Staples
- Season 14 Jackie Chan, Simon Pegg, Just Jack
- Season 14 Chris Tucker, Tori Spelling, Shiny Toy Guns
- Season 14 Glenn Close, Michael Cera, Modest Mouse
- Season 14 Claire Danes, Jonah Hill, Teddy Thompson
- Season 14 Cuba Gooding, Jr., Jackie Hoffman, Bruce Perry
- Season 14 Amanda Bynes, Judd Apatow, Straylight Run
- Season 14 Bob Saget, Maggie Q, Shane Mauss
- Season 14 Jeff Goldblum, Devon Aoki, Okkervil River
- Season 14 Kelly Preston, Ryan Reynolds, Ozomatli
- Season 14 Kevin Bacon, Will Forte, Eisley
- Season 14 Scarlett Johansson, Kevin Nealon, Locksley
Late Night with Conan O'Brien - Season 14 Episode 1 Julianne Moore, Aries Spears, Godsmack
7.05 62 minutes 
