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- Season 0 1998-09-16
- Season 1 1993-09-13
- Season 2 1994-09-12
- Season 3 1995-09-11
- Season 4 1996-09-17
- Season 5 1997-09-09
- Season 6 1998-09-15
- Season 7 1999-09-07
- Season 8 2000-09-05
- Season 9 2001-09-04
- Season 10 2002-09-03
- Season 11 2003-09-03
- Season 12 2004-08-31
- Season 13 2005-09-06
- Season 14 2006-09-05
- Season 15 2007-09-04
- Season 16 2008-09-02
Season 16 Episode
- Season 16 Jarod Miller, Jason Lezak, Ra Ra Riot
- Season 16 Nicolas Cage, Vivica A. Fox, Delta Spirit
- Season 16 Dr. Phil, Kevin Connolly, Adele
- Season 16 Jerry O'Connell, Tim Gunn, Christian Lander
- Season 16 Howie Mandel, Nastia Liukin, Bon Iver
- Season 16 Keira Knightley, Tyler Perry, Bill Burr
- Season 16 Curtis Jackson, Kaitlin Olson, Gym Class Heroes
- Season 16 Serena Williams, Amy Sedaris, Meiko
- Season 16 Eva Mendes, Luke Russert, The Fab Faux
- Season 16 Samuel L. Jackson, Ricky Gervais, Marc Broussard
- Season 16 Martha Stewart, Harland Williams, Kasey Chambers & Shane Nicholson
- Season 16 Ray Liotta, Marc Maron,Loudon Wainwright III
- Season 16 Anderson Cooper,Willie Nelson, Southside Johnny with La Bamba's Big Band
- Season 16 Ice-T, Dwayne Wade, Shane Mauss
- Season 16 Diane Lane, Patton Oswalt, Little Feat
- Season 16 Billy Bob Thornton, Aasif Mandvi, Kenny Shopsin
- Season 16 Jaime Pressly, Little Britain, Lenka Kripac
- Season 16 Julianne Moore, Zachary Levi, Jakob Dylan
- Season 16 Brooke Shields, Robert Reich, Amos Lee
- Season 16 Bill Maher, Simon Pegg, The Watson Twins
- Season 16 Julia Louis-Dreyfus, Michael Cera, Nate Bargatze
- Season 16 Robin Wright-Penn, Louis C.K., Department of Eagles
- Season 16 Tom Arnold, Flavor Flav, Ben Folds
- Season 16 Greg Kinnear. J.J. Abrams, Nick Cave and the Bad Seeds
- Season 16 Felicity Huffman, Jason Sudeikis, Jenny Lewis
- Season 16 Russell Crowe, Alicia Keys, Death Cab for Cutie
- Season 16 Molly Shannon, Jason Ritter, Noah McCullough
- Season 16 Dennis Quaid, Lance Mackey, Sarah McLachlan
- Season 16 LL Cool J, Oliver Stone, Dead Confederates
- Season 16 Christian Slater, Brian Posehn, Flobots
- Season 16 Harry Connick, Jr., Richard Lewis, O.A.R.
- Season 16 Bill Murray, Rob Corddry, Ray LaMontagne
- Season 16 Josh Brolin, Shaun Ellis & Helen Jeffs, Nikka Costa
- Season 16 Edward Norton, Chris "Ludacris" Bridges, Mike Birbiglia
- Season 16 Charles Barkley, Justin Long, Annuals
- Season 16 Tina Fey, Peter Sarsgaard, The Black Crowes
- Season 16 Tracy Morgan, Paget Brewster, The Last Shadow Puppets
- Season 16 Jada Pinkett-Smith, Jason Biggs, Pink
- Season 16 Mary-Kate Olsen, Will Forte, Tom Nardone
- Season 16 Brian Williams, Bill Bellamy, The Decemberists
- Season 16 Dennis Hopper, Katt Williams, Phil Lesh & Friends
- Season 16 Elvis Costello, Madeleine Albright, Lordi
- Season 16 Ricky Gervais, Vera Farmiga, Chromeo
- Season 16 Andy Richter, Jim Cramer, Tom Papa
- Season 16 Seth Green, Artie Lange, Conor Oberst & The Mystic Valley Band
- Season 16 Tom Brokaw, Frank Caliendo, Joshua Radin
- Season 16 Paul Rudd, John Stamos, Boz Scaggs
- Season 16 Masi Oka, Alan Zweibel, Rock of Ages
- Season 16 Snoop Dogg, Brian Regan, Blitzen Trapper
- Season 16 Jeff Corwin, Debra Messing, John Hodgman
- Season 16 Martin Short, Sarah Vowell, Margot and the Nuclear So & So's
- Season 16 Rosie O'Donnell, Becki Newton, Brian Wilson
- Season 16 Kiefer Sutherland, Rachel Maddow, Vampire Weekend
- Season 16 Hugh Jackman, Marge Klindera, Tom Morello
- Season 16 Kanye West, Seth MacFarlane
- Season 16 Ethan Hawke, Nikki Reed, Plain White T's
- Season 16 Stephen Colbert, Keri Russell, The Lee Boys
- Season 16 Hugh Laurie, Joel McHale, The Gaslight Anthem
- Season 16 Jennifer Connelly, Bradley Cooper, Alec Greven
- Season 16 Bill Hader, Jessica Szohr, Tony Bennett
- Season 16 Don Rickles, John Leguizamo, Erran Baron Cohen
- Season 16 Amy Adams, Eddie Izzard, John Legend
- Season 16 Eva Mendes, Ken Mink, Fleet Foxes
- Season 16 Jeff Goldblum, David Gregory, Charlie Viracola
- Season 16 Matthew Broderick, Paul F. Tompkins, Little Big Town
- Season 16 Jennifer Aniston, Judah Friedlander, Pilobolus
- Season 16 Carson Daly, Steve Schirripa, Bela Fleck and the Flecktones
- Season 16 Dustin Hoffman, Greg Giraldo, Old Crow Medicine Show
- Season 16 Benicio Del Toro, Sarah Chalke, Doyle & Debbie
- Season 16 Kate Hudson, Tim Daly, Bang Camaro
- Season 16 Chris Meloni, Sheriff Joe Arpaio, The Derek Trucks Band
- Season 16 Howie Mandel, Anthony Mackie, Lady Antebellum
- Season 16 Daniel Radcliffe, Dr. Drew Pinsky, Eric Hutchinson
- Season 16 Rosario Dawson, Donald Faison, Susan Tedeschi
- Season 16 Salma Hayek, Paul Bettany, Patty Loveless
- Season 16 Bob Costas, Fred Armisen, Robert Schimmel
- Season 16 Teri Hatcher, Aries Spears, Q-Tip
- Season 16 William H. Macy, Steve Nash, Los Straitjackets
- Season 16 Meredith Viera, Marc Maron, Fall Out Boy
- Season 16 Ron Howard,Eric McCormack & John Cassidy
- Season 16 John C. Reilly, Jimmie Johnson, The Walkmen
- Season 16 Matt Lauer, Steve Harvey, M83
- Season 16 Evangeline Lilly, Kevin Connolly, Cold War Kids
- Season 16 Jon Stewart, Mary Lynn Rajskub, Mike Birbiglia
- Season 16 Kathy Griffin, Paula Deen, Amy Lavere
- Season 16 Seth Meyers, Johnny Knoxville, Zac Brown Band
- Season 16 Jon Hamm, Ginnifer Goodwin, Theresa Andersson
- Season 16 Brian Williams, Taraji P. Henson, Nate Bargatze
- Season 16 Clive Owen, Judah Friedlander, Brett Dennen
- Season 16 Norm MacDonald, Gordon Ramsay, Levon Helm
- Season 16 Jimmy Fallon, Rose Byrne, John Pizzarelli
- Season 16 Alec Baldwin, Eliza Dushku, They Might Be Giants
- Season 16 Isla Fisher, The Jonas Brothers, Dan Auerbach
- Season 16 Bob Saget, The Newno2
- Season 16 Jason Sudeikis
- Season 16 Nathan Lane, Martha Stewart
- Season 16 Jerry Seinfeld, Craig Bierko
- Season 16 The Final Episode, The White Stripes
Late Night with Conan O'Brien - Season 16 Episode 45 Seth Green, Artie Lange, Conor Oberst & The Mystic Valley Band
7.05 62 minutes Tonight's guests include Seth Green and Artie Lange. Conor Oberst & The Mystic Valley Band perform.
